If you have 100 enchanting, you should be able to enchant at 25% without need of potions, etc., though you will still want enchanter's elixir for your protections.
When you enchant for fortify destruction, you're reducing the cost of the spell by 25% per piece of gear. So if you include fortify destruction in your helmet, armor, ring, and necklace, you will have reached a 100% discount. This means you can hurl the high-cost thunderbolts and incinerates all day long, without reducing your magicka one iota. This will help a lot, if you decide to use robes instead of armor, and will leave you plenty of magicka for mage armor or an atronach, or whatever you may wish to do.
Make sure you take the dual-enchant perk, have enough grand gems, and some enchanters elixirs on you. Here's how I would probably do it.
Helmet - fortify destruction, fortify magicka
Armor - fortify destruction, fortify conjuration
Necklace - fortify destruction, resist shock
Ring - fortify destruction, resist frost
Boots - muffle, resist fire
Gauntlets - fortify magicka, (and some other helpful amenity of your choosing. I usually have one-handed)
This gives you protection from the big 3 dragon/wizard attacks, plus silent movement, and 100% cost free destruction spells, plus a reduction on your conjuration. I think it's more important to have the reduced casting cost for the higher cost thralls than to regenerate quicker, since you will probably be regenerated before you have to cast it again.
The open spot on the gauntlets I usually fill with archery or one-handed, but you can add whatever you like from your list of available enchantments. If you're a nord or a dark elf, you will already have 50% frost or fire resistance, so you can use that slot in a ring or necklace for either extra magicka or some magicka regen. The storm thrall is the highest cost I've encountered so far, in the 500s. It's the only one I can't cast yet, unless I put on a magicka necklace. I'm not above carrying around an extra necklace, just to slip on when I conjure, and then replace with my "attack necklace."
Hope it helps.