I play it on acid, myself.
You can do that with a wireless keyboard if you like . I prefer being in my cozy office setup, the chair is comfortable and works for me. But I've got a friend who does all his PC gaming on his couch using a wireless keyboard with a touchpad and the 55" TV as his monitor.I play on PS3 too.
Got a gaming PC this christmas, that is capable of running skyrim on high settings but I always go back to PS3 lol...
I noticed that PC got way better graphics, mods, better performance and overall stuff, i dont even dislike using a mouse and keyboard...but nothing can replace playing skyrim on a big tv while laying down on the bed or a comfortable couch.