So far, I've gone a Khajiit assassin. I rocked Blade of Woe w/ a Daedric Dagger and a Daedric Bow. Focused on Sneak, a few points in One-handed, a decent amount of points in Archery, and Smithing and Enchanting to 100.
I also made something similar, except it was only an archer. Obviously, I majored in Archery, w/ a little in sneak to get the bonus damage. Same everywhere else except w/out one-handed. Also, both characters had high thief skills, like lockpicking and pickpocket.
Finally, I'm working on an Orc-Duelwielding Axes/Axe&Sword warrior. Heavy armor, one-handed, smithing, and enchanting. Oh, and lockpicking. Can't ever go wrong with lockpicking.