Depends. Are we talking Vampy LORDS or regular Vampies? I think it depends onsome factors:
What type of character are you? (Magic? Melee?)
Are you a Vampire Lord or regular Vampire?
Even though I'm generally a stealth-melee fighter, I prefer the VL. Ranged and Melee modes, awesome powwrs/perks, and a good boost when in dark (I think), I have raided whiterun and brought down all yhe non-essentials with nearly no damagr dealt, even though I was being mashed in the head by a small mob og essentials.