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Those graphics are pretty intense. You're most likely going to need a very powerful CPU and GPU if you're looking to play Skyrim like that with a high amount of FPS.
You're going to need a lot of power, that might be more than enough, 750w could probably hold you well but it's always good to have a bit extra.
And of course if your case doesn't have a HDD or CD ROM, you'll have to buy them seperate. All of this might go over your budget by a little bit, but if you actually bought all of this you'd have one beast of a machine. Would run whatever you throw at it with amazing FPS.
EDIT: Of course, the links included are for the UK Amazon site, but I just included them so you know exactly what product I'm referring to.
If your system gets any overheating problems, consider buying more fans and/or eventually liquid cooling if you are confident enough to set it up. You can also buy cases which are designed for smooth airflow.