My two would have to be these:
1) On another run, during The Golden Claw (a side quest I usually do first), while the three thieves were arguing about "What if Arvel doesn't come back?", I pulled out my bow and send the woman making the argument directly to Arkay. The other two stooges felt the need to perform a forensic investigation as to why she stopped talking and fell down, rather than investigate where that arrow came from - two more arrows later and they stood beside their female companion before Arkay, probably wondering how they got there...
2) Recently, I began a knight character, based on Game of Thrones - decided to focus on One-Handed Sword, Heavy Armor, Block, and Blacksmithing.
I chose to purchase Breezehome in Whiterun.
I decided to focus specifically on the following skills:
Heavy Armor
One-Handed (specifically one-handed swords)
Block
Smithing
Restoration
I did the Companions quest-line, then went on to the main game. At level 24, I slew Alduin!
Now, I am doing left over miscellaneous quests and am about to start Dawnguard (remember: my wolf blood gives me a 100% resistance to disease.)